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Sauna: Increases circulation Stimulates sweat Activates heat shock proteins Encourages metabolic turnover TUDCA: Supports bile flow Protects liver cells Reduces ER stress Enhances detox capacity Together, they may create a more coordinated response mobilizing compounds while supporting the pathways that eliminate them.* Reducing Cellular Stress While Increasing Detox Load Heat exposure temporarily increases oxidative stress

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Figure 6 Cerebral amyloid angiopathy (CAA) is a cerebrovascular disease, often associated with Alzheimer's dementia, which results from amyloid- accumulation on small blood vessel walls and often causes cerebral hemorrhage (Puy and Cordonnier, 2019)