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With the expiry of Novo Nordisks primary patent in India this March, Semaglutide the active ingredient in the Danish companys diabetes and anti-obesity drugs Ozempic and Wegovy emerged as one of the most commercially significant pharmaceutical molecules in the world, potentially creating a multi-billion-dollar opportunity for the Indian drug-making industry, which is the worlds third largest by volume and 11th largest by value

A 2025 comprehensive review in IJMS describes emerging delivery strategies including lipid nanoparticle-based mRNA therapies and CRISPR-dCas9 epigenetic editing to overcome BBB obstacles

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