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doi:10.1136/bmjopen-2018-026936 Monzani D, Genovese E, Rovatti V, Malagoli ML, Rigatelli M, Guidetti G

Enterohepatic circulation further influences LT4 metabolism, with conjugation via glucuronidation and sulfation in the liver, secretion into bile, and partial reabsorption by the intestinal flora (Eghtedari And Correa 2023)

The brain will try to compensate when a critical chemical is too high or too low for long periods of time

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