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Description

Acetylation of human mitochondrial citrate carrier modulates mitochondrial citrate/malate exchange activity to sustain NADPH production during macrophage activation

Triple mechanism: matrix + vessels + cells

Moreover, fecal microbiota transplantation (FMT) from healthy donors has been shown to ameliorate both amyloid pathology and cognitive deficits in murine models (Elangovan et al., 2022)