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Even if it seems like a good idea that should work, if the evidence isnt there, then such a treatment should only proceed in a setting that can generate the essential evidence. Jeff Levin-Scherz, M.D., the population health leader for health and benefits in North America at Willis Towers Watson, noted that GLP-1 drugs have been in use since 2005

doi: 10.1038/oby.2011.143

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Our data suggest a role for Y1-R on pancreatic -cell function, a role also suggested by other recent results 68 documenting up-regulation of Y1-R mRNA in brown adipose tissue, inguinal white adipose tissue, and skeletal muscle of obese mice and humans