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At present, the therapy of Parkinsons disease mainly uses dopamine agonists and MAO-B inhibitors to suppress the decomposition of dopamine, but they only target symptoms and have serious side effects (Jiang et al., 2015a)
Apart from the SOD1G93A transgenic animals, other models have been produced and shown to be deficient in EAAT2/GLT1 [383, 384]
Because GST binds reduced glutathione with high affinity, immobilization of glutathione on agarose enables efficient one-step purification of GST fusion proteins from crude lysates
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