27,37 Transcriptionally, regulators such as c-Myc, 38 E2F1, 39 and p53 40 can either positively or negatively modulate SIRT1 promoter activity
These new GLP-1RA medications suggest a tremendous and potentially life-changing opportunity for patients
Current Availability of GLP-1 Agonists As of August 2024, the availability of GLP-1 agonists varies 2 : In Stock: Ozempic, Mounjaro, Zepbound, and most strengths of Wegovy and Trulicity Limited Availability: Saxenda, certain strengths of Trulicity, Victoza, and the 0.25 mg/0.5 mL dose of Wegovy Even with the above shortages, our data suggests that the situation may not be as severe as portrayed in the media
Before starting any compounded GLP-1 therapy, confirm your chosen program uses licensed 503A pharmacies, documents safety protocols, and offers provider support lines