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The objective of this study was to examine the impact of two distinct compositions of PQ nanoparticles (one with chitosan and one without) on the oxidative condition of kidney tissues in rats that have been treated

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Key words : Glucagon-like peptide-1 Metabolic diseases Myostatin Obesity Sarcopenia GRAPHICAL ABSTRACT INTRODUCTION Metabolic syndrome is a cluster of conditions commonly associated with aging, such as insulin resistance and abdominal obesity, which can lead to complications including cardiovascular disease, hypertension, and type 2 diabetes.[1] This pathological condition is now considered an epidemic due to its rising global prevalence across all age groups, from children to adults.[2] A key challenge in managing metabolic syndrome is the absence of a single drug that can treat the disease due to its multifactorial nature.[3] As a result, most available medications for metabolic syndrome can only target one or more of its components but cannot fully eradicate the syndrome