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Genetic deletion or pharmacological inhibition of STING in transgenic mouse models reduced A plaque burden, diminished harmful pro-inflammatory signaling, and protected cognitive function

Additionally, further investigations are underway to explore potential additional uses of tirzepatide in the clinical management of other cardiometabolic conditions associated with obesity, including heart failure and non-alcoholic (or metabolic-dysfunction associated) steatohepatitis (NASH/MASH)

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Lowering of hemoglobin A1C and risk of cardiovascular outcomes and all-cause mortality, a meta-regression analysis