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Gut microbiota disorders can increase LPS release, leading to higher intestinal permeability and activation of gastrointestinal immune cells to release inflammatory cytokines (319, 320)

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Nuzum E, Medeisyte R, Desai R, Tsipa A, Fearn C, Eshetu A, Charlesworth G, Stewart GR, Crutch SJ, El Baou C, Kurana S (2025) Dementia subtypes and suicidality: a systematic review and meta-analysis