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No significant changes in blood pressure, heart rate, electrocardiographic findings, serum chemistry or urinalysis were noted and no significant changes were observed in the results of the Profile of Mood States Questionnaire for fatigue or vigor

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Limitations and Considerations: Single center and relatively small cohort (n = 29) Burdensome protocol including an invasive procedure, implanted device, and multiple follow-up visits No direct assessment of baseline activity levels or exercise tolerance prior to enrollment Reddy YNV, Koepp KE, Carter R, et al

Supporting these processes may contribute to overall cellular health maintenance