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Angle the needle against the vial wall and release the diluent slowly down the glass, not directly onto the lyophilized cake

The compound progressed through Phase 2 trials under multiple sponsors for postoperative ileus and related gastric-motility indications, with one randomized controlled trial published in 2014, but did not advance to a marketed therapeutic in any major jurisdiction

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A randomized controlled trial comparing colonic irrigation and oral antibiotics administration versus 4% formalin application for treatment of hemorrhagic radiation proctitis