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A controlled trial that included 90 subjects with NAFLD found those treated with 303 mg silibinin along with 10 mcg (400 IU) vitamin D and 15 mg vitamin E, twice daily for six months, were more likely to improve with regard to metabolic markers, oxidative stress, endothelial function, and NAFLD progression compared with those who were untreated

This is due to the improper use of the injections, which can be due to the following reasons