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Feig JE, Rong JX, Shamir R, Sanson M, Vengrenyuk Y, Liu J, Rayner K, Moore K, Garabedian M, Fisher EA

7 , e000387 (2020)

(Source 1) Suboptimal and deficient glutathione levels are associated with aging and an increased risk for chronic diseases, including: Mitochondrial dysfunction Neurodegenerative disease, including Alzheimers and Parkinsons disease Cancer Chronic liver disease Metabolic disease, including diabetes and hypertension Cardiovascular disease Pulmonary Infertility Autoimmune diseases, including lupus and multiple sclerosis Mental health disorders Cystic fibrosis (Source 1, 2) A viral illness, including SARS-CoV-2, the virus that causes Covid-19, can also cause glutathione deficiency

Acetylation abundance across phenotypes (n = 162 patients)