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Microbiomics, the scientific study of microbial communities and their interactions with the host, has gradually revealed that gut microbes may affect joint health through various mechanisms in OA research

It can assist in precise cancer diagnosis, targeted drug delivery, and improved therapeutic efficacy [108, 109]

A lowered antioxidant status has been noted as one of the causes of depression, in addition to lower glutathione peroxidase activity (they play into each other)

Acknowledgements We would like to acknowledge the researchers whose relevant works are cited in this review and all co-authors for their support