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Van Rompuy AS, Oliveras-Salv M, Van der Perren A, Corti O, Van den Haute C, Baekelandt V (2015) Nigral overexpression of alpha-synuclein in the absence of parkin enhances alpha-synuclein phosphorylation but does not modulate dopaminergic neurodegeneration

If labs are stable, proceed to the next dose increase

Suitability isnt determined by weight or BMI alone

For example, in 2023, the FDA approved Wegovy (semaglutide) for chronic weight management in adults with BMI 30 kg/m or 27 kg/m with comorbidities, based on robust data from the STEP trials showing up to 17.4% mean weight loss from baseline over 68 weeks