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These metabolites include cytochrome P450 metabolites of arachidonic acids 20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids, cyclooxygenase metabolites prostaglandin E2, prostaglandin I2, and thromboxane A2, and lipoxygenase metabolites leukotrienes, hydroxyeicosatetraenoic acids, and lipoxins

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