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For people living with MS, this is especially important because: If you are taking a GLP-1 medication, protecting muscle and bone health becomes an important part of your overall care plan

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Protein analysis of biopsy samples Muscle biopsy samples were allocated for protein determination by western blot analysis with antibodies (New England BioLabs, Mississauga, ON, Canada) against total and the phosphorylated protein targets: mTOR, phospho-mTOR (Ser2448), p70-S6K, phospho-p70-S6K (Thr389), 4E-BP1, and phospho-4E-BP1- (Thr37/46)

Thus, SYNCRIP may regulate ferroptosis through broader pathways beyond GPX4, underscoring the need for further investigation to elucidate the precise molecular pathways involved