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Scleroderma affects the skin and other structures, causing the formation of scar tissue

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The change in bone age, for those with measurements after at least 1 year of treatment up to a maximum 17 years of treatment, exceeded the change in chronological age by a mean of 0.9 years (SD = 1.8) (+ 7.4 years [SD = 3.7] versus + 6.5 years [SD = 3.7], respectively)