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These are typified by the following two enzymes: Methylmalonyl-CoA mutase [edit] Methylmalonyl coenzyme A mutase (MUT) is an isomerase enzyme that uses the AdoB 12 form and reaction type 1 to convert L-methylmalonyl-CoA to succinyl-CoA, an important step in the catabolic breakdown of some amino acids into succinyl-CoA, which then enters energy production via the citric acid cycle

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This approach delivers the peptide directly into the joint space, concentrating its effects at the site of cartilage damage, synovial inflammation, or tendon injury within the joint, rather than relying on systemic diffusion from a subcutaneous injection site