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Note that this was just supplementation alone and not combined with weight lifting or exercise.[ref] In a study involving both young athletes and untrained, middle-aged adults, carnitine supplementation increased carnitine levels in the muscles.[ref] For acute aerobic performance, oral supplementation with 1-3g/day of carnitine gives a slight edge, but it doesnt affect more moderate intensity athletic performance.[ref] Supplemental L-carnitine in old age: Access this content: An active subscription is required to access this content

For people with T2D, a phase 2 trial showed that 12 weeks of efinopegdutide achieve up to 7.9% WL (compared to 0.7% WL with placebo) without actual improvement in HbA1c [78]