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Recommended protocol: Washout: 25 to 30 days Starting dose: 2mg weekly Week 5: escalate to 4mg Week 9: escalate to 8mg Week 13: escalate to 12mg based on response This accelerated schedule saves 4 weeks compared to the standard titration

Progress is monitored monthly by your provider, allowing dosage adjustments necessary to maintain ongoing, sustainable weight loss

The SURMOUNT-1 trial , published in the New England Journal of Medicine , showed tirzepatide at its highest dose achieved average weight reductions of 22.5% over 72 weeks making it the most effective FDA-approved weight loss medication available

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