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BPC 157 and the central nervous system BPC 157 was found to have a direct therapeutic effect (i.e., counteracting hippocampal ischaemia/reperfusion-induced damage) in rats following stroke

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The only published dosing protocol is from mouse studies: 5 mg/kg by intraperitoneal injection, given intermittently over weeks

Further experiments have demonstrated that the peptide is capable of suppressing the activity of pro-inflammatory and fibrotic factors characteristic of the senescence-associated secretory phenotype (SASP), thereby contributing to the restoration of damaged tissue microenvironments