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The covalent modification of STAT1 cysteines by sulforaphane promotes antitumor immunity via blocking IFN--induced PD-L1 expression
Furthermore, sourcing introduces uncertainty in sterility and formulation integrity, which may represent a more immediate and clinically relevant risk than theoretical biologic effects, particularly given the potential for nonsterile preparation, contamination, or inconsistent formulation in nonregulated injectable products
It is especially concentrated in white blood cells and platelets, which release it at sites of injury to initiate the repair cascade
Importantly, these body weight changes were not attributable to differences in food intake across the groups, as all treatments showed similar food consumption patterns in both lean and obese mice
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