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Coronary and arterial plaque (atherosclerosis) develops gradually as cholesterol particles such as LDL in the blood are "lipid oxidized" and damage the blood vessels' lining, forming a plaque

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Special situations: diabetes, age 60+, plant-based, and strength training Type 2 diabetes patients on a GLP-1 generally use the same 1.01.5 g/kg/day band, with the caveat that protein at breakfast can blunt morning glucose spikes so front-loading has a second benefit beyond muscle preservation