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But the gap between the two compounds may narrow in real-world settings where adherence and dose optimization are less consistent

The factors that lead to depletion of glutathione includes natural ageing process, or the external stressors that include chronic exposure to chemical toxins, cadmium exposure, alcohol use, smoking, pollution, strenuous aerobic activities, dietary factors, ultraviolet (UV) radiation exposure, tissue injury as from burns, ischemia, septic shock, surgery, drugs (such as acetaminophen and adriamycin)

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Mechanical loading of the intervertebral disc: from the macroscopic to the cellular level