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De Hollanda BA, Prizo VM, de Souza MD, et al

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FOXO4-DRI has been suggested to prevent normal FOXO4 binding to p53, eliminate senescent cells, enhance organ function, and reduce cell death progression

A new briefing from the Californian-based think tank Pacific Research Institute (PRI) warns that continued large-scale sales are not only putting patients at risk but could wipe out between $9.3bn and $11.8bn in future R&D investment enough to cost the world four to five new medicines