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Beyond PT-141 Peptide applications in sexual motivation research, MC4R is under active investigation for: Obesity and energy homeostasis MC4R knockout mice display severe obesity, establishing the receptors critical role in metabolic regulation Inflammation modulation MC3R has been implicated in anti-inflammatory signaling Neuropsychiatric research dopaminergic crosstalk with melanocortin pathways intersects with addiction, reward, and mood research This makes PT-141 Peptide not only relevant to sexual health research but also a probe compound for understanding the broader melanocortin system in preclinical studies

Last month, Zealand Pharma announced positive top-line results from a phase 1b trial of its weight loss drug, a GLP-1/GLP-2 receptor dual agonist called Dapiglutide

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