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doi: 10.1099/00207713-51-1-39 158 Lo SassoGKhachatryanLKondylisABatteyJNDSierroNDanilovaNAet al

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DAO uses copper as a cofactor and requires vitamin B6 (in its P5P form) to function optimally. 24 Multiple SNPs in AOC1 have been associated with significantly reduced DAO activity and histamine intolerance