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If there is no response, corticosteroids are used in conjunction with other immunosuppressive agents, such as infliximab or mycophenolate, depending on site of irAE and severity

Free Radic Biol Med 2015

Pretreatment with exogenous glutathione to old rats led to a significant increase in total glutathione content by 40% ( p = 0.0027) compared to old untreated rats (Figure 1A)