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In humans and other mammalian species, the liver is also the main site of the production of bile acids (BAs), ketone bodies (KB), and lipids ( Figures 1 , 2 )

Key Takeaways 5-Amino-1MQ is a small-molecule quinolinium compound rather than a peptide

Li J, Wang Q, Yang Y, Lei C, Yang F, Liang L, Chen C, Xia J, Wang K, Tang N (2019) GSTZ1 deficiency promotes hepatocellular carcinoma proliferation via activation of the KEAP1/NRF2 pathway

The exact role of such complex comorbid conditions to altered AED response over time is unclear, although the longer-term, concomitant detrimental effects of OS, neuroinflammatory and synaptic dysfunction are common targets that could be further exploited therapeutically