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Based on the results of the short-term model, 20 g liraglutide was selected, and the potential benefit of liraglutide in OA-associated pain was assessed using the von Frey test (Fig

But GLP-1 also has an indirect effect on the liver (by lowering hepatic gluconeogenesis) and the brain (by increasing neuroprotection) [56]

Weeks 8 through 16: appetite suppression at therapeutic levels As the dose climbs to 1.0 mg, 1.7 mg, and eventually 2.4 mg, the appetite suppression deepens