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Researchers with a history of pancreatitis, medullary thyroid carcinoma, or MEN2 syndrome should avoid both compounds due to the GLP-1 receptor activation component

Response: As described in the CY 2026 PFS proposed rule (90 FR 32676), an ACO that is eligible for the health equity adjustment may receive up to a maximum of 10 additional points that are added to its MIPS quality performance category score, the sum of which then becomes the ACO's health equity adjusted quality performance score

For most outcomes, the risks appeared similar between the groups with no definitive increase apparent for continued medication use