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Kirkland JL, Tchkonia T (2020) Senolytic drugs: from discovery to translation

Cryo-CLEM INS-1 832/3 SNAP/FLAG-hGLP-1R cells previously transfected with EGFP-VAPB were plated onto glow discharged (30 seconds, 20 mA) poly-L-lysine-coated Quantifoil R2/2 200 mesh gold EM grids (Electron Microscopy Sciences)

While most hydration challenges on GLP-1 therapy can be managed with increased fluid intake and dietary modifications, certain situations require prompt medical evaluation to prevent serious complications or identify underlying issues requiring treatment adjustment