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Retatrutide adds glucagon receptor activation on top of that, producing the most significant weight loss of any peptide studied to date

this putative protective effect appears to be associated with the absence or marked reduction of red blood cell accumulation in the liver, although a causal relationship cannot be established from the available data

References: [1]Schebb, Nils Helge

However, this same delay in gastric emptyingcalled gastroparesis when severecan worsen symptoms in patients whose stomach lining is already inflamed from gastritis