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This suggests that hydraulic resistance could significantly impact cell migration and decision-making in vivo

Science Advances , 7 (17)

Because we finalized significant methodological and data source changes to the MEI in the CY 2023 PFS final rule and significant time had elapsed since the last rebasing and revision of the MEI in CY 2014, we believed that delaying the implementation of the finalized 2017-based MEI was consistent with our efforts to balance payment stability and predictability with incorporating new data through more routine updates

When a compound binds to a target protein in vivo , any unbound compound must be rapidly eliminated to avoid off-target effects