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To date, the most detailed study of lipid mediators in DES has focused on eicosanoids, which were profiled in the TF of healthy individuals, in comparison with MGD patients, by means of an MS-based approach [45]

For example, ROS is eliminated by reduced glutathione (GSH), which serves as a reducing agent

In addition, Ferroptosis is also associated with mitochondrial dysfunction, including changes in mitochondrial membrane potential and alterations in mitochondrial morphology, known to produce ROS, further exacerbating lipid peroxidation [4]