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If you are below the maximum 12mg dose and experiencing a genuine plateau lasting more than 4 weeks, dose escalation is often the most effective intervention

16.1%) Tirzepatide was superior on all five key secondary endpoints A post-hoc cardiovascular analysis published in European Heart Journal Open (September 2025) found tirzepatide was also associated with a greater predicted 10-year cardiovascular risk reduction an absolute reduction of 2.4% vs