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This is crucial because chronic, low-grade inflammation is a primary driver of insulin resistance

Copyright 2014 Korean Diabetes Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited

Thus, specifically targeting the intercellular communication between macrophages and -cells offers a unique strategy to prevent/halt the islet inflammatory events underpinning T1D and T2D

315 Spontaneous Bacterial Peritonitis Ascites predisposes to spontaneous bacterial peritonitis, defined as bacteremia (typically gram negative), in the absence of mechanical disruption of the bowel