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If the bioregulator framework is correct (peptide triggers a cascade that persists after clearance), pulsed dosing should theoretically work though its been studied less than the daily protocols

"Fortunately, most of the side effects are reversible, but early recognition and proper treatment are critical." To the develop the guidelines, ASCO and NCCN convened multidisciplinary panels with representation from medical oncology, dermatology, gastroenterology, rheumatology, pulmonology, endocrinology, urology, neurology, hematology, emergency medicine, and nursing, as well as patient advocacy experts

One of these is the family of trefoil factor peptides. The trefoils are peptides that are protected from degradation in the stomach by their complex, twisted structure

doi:10.1002/ptr.2712