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Description

In all three cell lines IGF-1 caused significant TAP1 , TAP2 and ERAP1 downregulation, accompanied in Myc-CaP by downregulation of TAP binding protein Tapbp (Fig

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While the preclinical safety profile appears favorable (few adverse effects reported in animal studies), this does not guarantee the same in humans, especially with prolonged use

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doi: 10.1152/ajpregu.00442.2002

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