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Besides the intracapsular and intraseptal location of the nests, perhaps the more important features that will help the pathologist make the right call is the benign cytologic and nuclear features of the nevic cells when compared with the epithelioid melanoma cells with nuclear hyperchromasia and pleomorphism

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This highlights a significant knowledge gap regarding the genetic profiles and specific characteristics of these populations, which could be linked to their higher PCa mortality rates and represent potential areas for the implementation of preventive and/or therapeutic measures