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The most frequently used tests involve the measurement of plasma concentrations of endogenously produced compounds, such as bilirubin and bile acids, and determination of the rate of clearance of exogenous compounds, such as aminopyrine, lidocaine, and caffeine

The applicant notes that if another manufacturer were to seek FDA approval for adjuvant use of sargramostim but was not involved in its production, the available single-dose 250-mcg vial presentation of Leukine would likely not be optimized for the small doses being studied in these trials

K., Streu, C

It eliminates the most common dosing errors that researchers make when working with any reconstituted peptide solution