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Vitamin B12 is best injected intramuscularly into the deltoid (upper arm), thigh, or gluteal muscle (buttocks)

You push the needle past the subcutaneous layer and into the joint capsule

Neither is "better" in a research sense, because the two are studied for different mechanistic questions

If your 100mg vial costs $80-150 (common retail range): At 1mg daily: $0.80-1.50 per dose At 2mg daily: $1.60-3.00 per dose At 3mg daily: $2.40-4.50 per dose At 5mg daily: $4.00-7.50 per dose Compared to clinic-administered GHK-Cu treatments costing $50-200+ per session, self-administered research protocols offer substantial cost advantages