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Notice also that the p K a scale is logarithmic, so even a small difference, lets say p K a 1 = 16 and p K a2 = 19, represents 3 p K a units, which means the first compound is 10 3 or 1,000 times more acidic than the second compound

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This criterion ensured consistent capture of baseline BMI, comorbidity, and prescription data from the start of each patients record and reduced misclassification of prior GLP-1 RA exposure

The push for regulatory change is being amplified by attorneys involved in the New Jersey multicounty litigation effort, who argue that Novo Nordisk has long been aware of this potential risk but has failed to update its labeling accordingly