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Description

PLoS One 7, e29968

C.SimpsonK

Senescence induction in colon (HTC116) and bladder (EJ) cancer cell lines, followed by an incubation with the B2M-ADC, led to the clearance of 35% of senescent cells

[3] Animal (preclinical, limited to potency/anabolism studies): Rodent studies from the 1990s demonstrated that Long R3 IGF-1 and related IGFBP-resistant analogs are more anabolically potent than native IGF-1 per dose