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The most effective approach is lifestyle changes, including a healthy, calorie-controlled diet and regular exercise

10.1096/fj.201700602R [DOI] [PubMed] [Google Scholar] Zhang L., Yang S

Upstream iron metabolism genes (such as FPN, TFR1, and DMT1) can influence the occurrence and development of ferroptosis 25,26,27,28 , but how does the downstream pathway change

It is important to note these trials were not head-to-head comparisons, and real-world outcomes may differ based on adherence, lifestyle, and individual response