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Originally identified in human plasma, GHK readily binds copper (II) ions to form the biologically active GHK-Cu complex, which has been extensively studied across regenerative biology, including skin physiology, connective tissue maintenance, wound healing and healthy ageing

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A comprehensive review of the main lignan components of Schisandra chinensis (north Wu wei zi) and Schisandra sphenanthera (south Wu wei zi) and the lignan-induced drug-drug interactions based on the inhibition of cytochrome P450 and p-glycoprotein activities