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Nat Rev Immunol 2023, 23: 3854

Mechanisms: How GLP1 Might Influence Mood Several mechanisms have been proposed to explain how GLP1 receptor agonists could impact brain function and mood regulation

Important safety considerations include the risk of acute pancreatitis (seek urgent medical attention for severe, persistent abdominal pain), gallbladder disease, and potential worsening of diabetic retinopathy, particularly in patients with pre-existing retinopathy who experience rapid improvement in blood glucose control