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IL-8 (inflammatory markers), tissue oxygenation, matrix metalloproteinases (1, 2, 3, 9, 12), cell survival & proliferation, DNA damage etc
revealed that in an ISO-mediated model of myocardial infarction, direct overexpression of the Nrf2 gene enhanced GSH levels in cardiomyocytes and guarded cardiomyocytes against oxidative damage and lessened the occurrence of ferroptosis [202]
Furthermore, when taken in conjunction with conventional therapy, the occurrence of adverse drug reactions (ADRs) has been significantly reduced
A 2026 study in Cell Reports Medicine found that GLP-1 medications predominantly reduce body fat, with a smaller but significant decrease in lean mass
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